The main event begins at 4am BST, but the fight itself may start closer to 5am.
While the times haven't been announced, it will certainly be a late night or very early start for viewers in the UK, so expect to be up well into Sunday 27 August, and possibly calling in sick on Monday 28.
Crowds will pack the T-Mobile arena but millions more will be glued to the fight via TV around the world.
What TV channel is the fight on?Sky Sports will show the fight on their Box Office channel for £19.95.
They will broadcast it via their pay-per-view service live from Las Vegas on August 26.
In the US, on the other hand the channel and staggering sum to watch it has been revealed.
It will cost £77.60 ($99.99) to watch on Showtime PPV in America in HD, £69.85 ($89.99) in standard definition.
How can I live stream the fight?Sky Sports Box Office now allows you to stream the fight live via a PC/Desktop/MAC, NOW TV box, iPhone, iPad, Android phone or Android tablet for £19,95. Click here for full Sky Sports’ full terms and conditions for the fight.
It makes it very simple for fans as all you have to do is sign up, make the transaction and watch the fight unfold.
Once you’ve paid, you can then select which viewing online/device you want to watch the fight on using the same login details created at sign up (i.e e-mail address and password).
You cannot watch the event through a Sky or Virgin box if purchased to stream online or via the Box Office apps.
Click here to create a Sky Sports account to stream the fight.